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Chemotherapy Agents Essay Assignment Paper
Question
A. Pertuzumab
B. Cyclophosphamide
C. Trastuzumab
D. Doxorubicin
Doxorubicin is the most likely to necessitate a recommendation for a central line placement among the listed chemotherapy agents.
EXPLANATION
Chemotherapy agents can be classified based on their potential to cause damage to tissues if they leak out of the vein during administration. Vesicants are chemotherapy agents that can cause severe tissue damage, including blistering, necrosis, and scarring, if they extravasate or leak out of the vein and into the surrounding tissues. The extent of damage can vary based on the type and amount of vesicant agent, the rate and volume of infusion, and the location of the extravasation.
Doxorubicin is a potent vesicant that can cause significant damage if it leaks out of the vein during administration. As such, it is recommended that it be administered through a central line, which is a catheter placed directly into a large vein in the chest or arm. This allows for the medication to be infused into a larger, more stable vein, reducing the risk of extravasation and tissue damage Chemotherapy Agents Essay Assignment Paper
Step 2/2
Other options:-
The other options are wrong because they are not typically associated with significant vesicant properties, and therefore, they do not require central line placement.
Pertuzumab is a monoclonal antibody used to treat breast cancer. It is not known to cause significant tissue damage if it leaks out of the vein, and therefore, it does not require central line placement.
Cyclophosphamide is a chemotherapy drug used to treat a variety of cancers. Although it can cause irritation to the veins, it is not typically associated with significant vesicant properties, and therefore, it does not require central line placement.
Trastuzumab is a monoclonal antibody used to treat breast and stomach cancers. It is not known to cause significant tissue damage if it leaks out of the vein, and therefore, it does not require central line placement.
Final answer
In conclusion, the correct answer is D. (Doxorubicin).
Doxorubicin is the most likely to necessitate a recommendation for a central line placement among the listed chemotherapy agents. Doxorubicin is a potent vesicant that can cause significant tissue damage if it leaks out of the vein during administration. Therefore, it is recommended that doxorubicin be administered through a central line to minimize the risk of extravasation and tissue damage. Cyclophosphamide, trastuzumab, and pertuzumab are not typically associated with significant vesicant properties, and therefore, they do not require central line placement Chemotherapy Agents Essay Assignment Paper
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